AFM24 是 CHO 表达的、具有 TandAb 结构的双特异性抗体，靶向 EGFR&Fc-gamma-RIIIA。AFM24 带有 huIgG1-SCFV 型重链和 λ 型轻链，其预测的分子量 为 74.5 kDa。AFM24 的同型对照可参考 Human IgG1 kappa, Isotype Control。

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The detected molecular weight of Anti-EGFR & CD16a/Fc-gamma-RIIIA Reference Antibody (Afm24) is 196.31 kDa.

Anti-EGFR & Fc-gamma-RIIIA Reference Antibody (AFM24) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 99.5%.

The purity of Anti-EGFR & Fc-gamma-RIIIA Reference Antibody (AFM24) is 97.37%, determined by SEC-HPLC.

Afm24 bound to EGFR protein, and then rebounded to secondary antibodies (Anti-human-IgG-Fc-HRP) , and read OD450. As shown in fig, Afm24 bound hu-EGFR-His, and the EC50 was 0.044 nM.

Afm24 bound to CD16a protein, and then rebounded to secondary antibodies (Anti-human-IgG-Fc-HRP) , and read OD450. As shown in fig, Afm24 bound hu-CD16a-His, and the EC50 was 0.489 nM.

Afm24 bound to EGFR-CHO-K cells, and then rebounded to fluorescent secondary antibodies (Anti-human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Afm24 bound to EGFR-CHO-K cells, and the EC50 was 4.075 nM.

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