Tobemstomig 是一种抗 PDCD1/LAG3 的人源 IgG1 κ 单克隆抗体。Tobemstomig 的同型对照产品：Human IgG1 kappa, Isotype Control。

For Powder, reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

本产品仅用作科学研究！

The detected weight of Anti-LAG-3 & PD-1 Reference Antibody (Tobemstomig) is 145.01 kDa.

Anti-LAG-3 & PD-1 Reference Antibody (Tobemstomig）on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

The purity of Anti-LAG-3 & PD-1 Reference Antibody (Tobemstomig）is 94.61%, determined by SEC-HPLC.

Tobemstomig bound to LAG-3 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Tobemstomig bound human LAG-3 Protein-His, and the EC50 was 0.2401 nM.

Tobemstomig bound to PD-1 protein, and then rebounded to secondary antibodies(Anti-Human-IgG-Fc-HRP) , and read OD450. As shown in fig, Tobemstomig bound human PD-1 Protein-His, and the EC50 was 0.02504 nM.

Tobemstomig bound to huPD-1-Jurkat cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Tobemstomig bound to huPD-1-Jurkat cells, and the EC50 was 1.222 nM.

Tebotelimab bound to huLAG-3-CHO-K cells, and then rebounded to fluorescent secondary antibodies(Anti-Human IgG, Fcγ PE) , and test by flow cytometry. As shown in fig, Tebotelimab bound to huLAG-3-CHO-K cells, and the EC50 was 8.727 nM.

-80°C for 2 years under sterile conditions；-20°C for 1 year under sterile conditions；Avoid repeated freeze-thaw cycles.