Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 'Arg-4' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation.

推荐稀释比 WB: 1/500-1/1000  IHC: 1/50-1/100  IF: 1/50-1/200  ChIP: 1/20

Western

Western blot analysis of PRMT1 in (1) HeLa lysates; (2) NIH/3T3 lysates; (3) PC-12 lysates using PRMT1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。