This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

推荐稀释比 WB: 1/500-1/1000  IHC: 1/100-1/200  FC: 1/50-1/100   ELISA: 1/10000

Western

Western blot analysis of PAX8 in  HL-60 (1), HEK293 (2), Raji (3), Hela (4), Jurkat (5), A431 (6), A549 (7), and K562 (8) cell lysate using PAX8 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded human kidney tissues using PAX8 antibody.

Flow

Flow Cytometry analysis of  SK-OV-3 cells using PAX8 antibody (green) and negative control (red).

-15到-25度