Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2.

Western

Western blot analysis of Prdx 1 in T47D, 3T3, COS7, C6 and Hela lysates using Prdx 1 antibody.

Immunofluorescence

Immunofluorescence analysis of Peroxiredoxin 1 (6A6) in Hela using Peroxiredoxin 1 (6A6) antibody(left) ,and DAPI (blue).

Western

Western blot analysis of Peroxiredoxin 1 (6A6) in MCF-7, rat Kidney , mouse Brain lysates using Peroxiredoxin 1 (6A6) antibody.

Western

Western blot analysis of Peroxiredoxin 1 (6A6) in urkat, CHO-K1, C6, Hela lysates using Peroxiredoxin 1 (6A6) antibody

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using Peroxiredoxin 1/PAG (6A6) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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