Polydatin作为一种从虎杖根中提取的传统中药成分，在多种实验模型中表现出抗炎活性。该化合物通过抑制葡萄糖-6-磷酸脱氢酶（G6PD）活性，进而诱导氧化应激与内质网应激反应。
| 英文别名 (English Synonym) | Polydatin |
| 中文名称 (Chinese Name) | 虎杖苷 |
| 靶点 (Target) | Phospholipase (e.g. PLA) |
| 通路 (Pathway) | Natural Products |
| CAS号 (CAS NO.) | 27208-80-6 |
| 分子式 (Formula) | C20H22O8 |
| 分子量 (Molecular Weight) | 390.39 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
[1] Mele L, Paino F, Papaccio F, Regad T, Boocock D, Stiuso P, Lombardi A, Liccardo D, Aquino G, Barbieri A, Arra C, Coveney C, La Noce M, Papaccio G, Caraglia M, Tirino V, Desiderio V. A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo. Cell Death Dis. 2018 May 1;9(5):572. doi: 10.1038/s41419-018-0635-5. PMID: 29760380; PMCID: PMC5951921. [2] Wang HL, Cui XH, Yu HL, Wu R, Xu X, Gao JP. Synergistic effects of polydatin and vitamin C in inhibiting cardiotoxicity induced by doxorubicin in rats. Fundam Clin Pharmacol. 2017 Jun;31(3):280-291. doi: 10.1111/fcp.12258. Epub 2017 Jan 24. PMID: 27891661.
