Bithionol (Actamer)，又称硫双二氯酚、硫氯酚或别丁，是可溶性腺苷酸环化酶(adenylyl cyclase)抑制剂，通过与变构激活位点结合有效抑制人可溶性腺苷酸环化酶，IC₅₀为4 μM，具有抗菌活性，常用作驱虫药，临床上用于治疗肺吸虫病。

参考文献

[1] Silke Kleinboelting, et al. Bithionol Potently Inhibits Human Soluble Adenylyl Cyclase through Binding to the Allosteric Activator Site. J Biol Chem. 2016 Apr 29;291(18):9776-84.

[2] Florent RL, et al. In vitro toxicity of bithionol and bithionol sulphoxide to Neoparamoeba spp., the causative agent of amoebic gill disease (AGD). Dis Aquat Organ. 2010 Sep 17;91(3):257-62.

[3] J Maki, et al. Anthelmintic effects of bithionol, paromomycin sulphate, flubendazole and mebendazole on mature and immature Hymenolepis nana in mice. J Helminthol. 1985 Sep;59(3):211-6.

冰袋运输。粉末直接保存于-25~-15℃，有效期3年。建议分装后-25~-15℃干燥保存，避免反复冻融。