Chlorpromazine hydrochloride (Chlorpromazine HCl, Sonazine)，又称盐酸氯丙嗪，是一种多巴胺和钾离子通道抑制剂。Chlorpromazine Hydrochloride与D2和5HT2A结合的Ki分别为363 nM和8.3 nM。

参考文献

1.Lee SJ, et al. Mechanism of inhibition by chlorpromazine of the human pain threshold sodium channel, Nav1.7. Neurosci Lett. 2017 Feb 3;639:1-7.

2.Kale OE, et al. An L-type calcium channel blocker, protects against chlorpromazine-induced neurobehavioural deficits in mice. Fundam Clin Pharmacol. 2017 Jun;31(3):329-339.

3.Sampaio LR, et al. Electroencephalographic study of chlorpromazine alone or combined with alpha-lipoic acid in a model of schizophrenia in rats. J Psychiatr Res. 2017 Mar;86:73-82.

4.Suzuki H, et al. Comparison of the anti-dopamine D2 and anti-serotonin 5-HT(2A) activities of chlorpromazine, bromperidol, NSC 170973 and second-generation antipsychotics parent compounds and metabolites thereof. J Psychopharmacol. 2013 Apr;27(4):396-400.

5.Thomas, D, et al. The antipsychotic drug chlorpromazine inhibits HERG potassium channels. Br J Pharmacol,2003 Jun;139(3):567-74.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。