L-抗坏血酸-2-磷酸三钠盐 维生素C衍生物|Sodium L-ascorbyl-2-phosphate|CAS 66170-10-3（53585ES）

Sodium L-ascorbyl-2-phosphate (L-Ascorbic acid 2-phosphate trisodium, 2-Phospho-L-ascorbic acid trisodium, Sodium ascorbyl phosphate, SAP)，也称L-抗坏血酸-2-磷酸三钠盐或维生素C磷酸酯钠，是一种维生素C衍生物，有抗氧化活性，能够促进肝细胞生长因子(HGF)的产生，促进胶原蛋白的表达和形成。Sodium L-ascorbyl-2-phosphate还可作为碱性磷酸酶催ALP化底物，ALP表达异常与癌症、糖尿病和肝脏功能障碍等多种疾病相关。

参考文献

1.Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7;52(12):8711-7.

2.Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25;266(15):9997-10003.

3.Kyllönen L, et al. Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.Stem Cell Res Ther. 2013 Feb 15;4(1):17.

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