阿司匹林Aspirin(NSC 27223 乙酰水杨酸) COX-1/COX-2抑制剂|CAS 50-78-2（53526ES）

Aspirin (Acetylsalicylic acid, NSC 27223, NSC27223, ASA)，又称阿司匹林、乙酰水杨酸或邻乙酰水杨酸，是非甾体类抗炎药，一种可口服不可逆的环氧合酶COX-1/2有效抑制剂，IC₅₀分别为5和210 μg/mL。阿司匹林常用作止痛药，还有抗血小板聚集作用，可预防冠状动脉和脑血管血栓形成。

参考文献

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2.Grilli M, et al. Neuroprotection by aspirin and sodium salicylate through blockade of NF-kappaB activation.1996 Nov 22;274(5291):1383-5.

3.Gao Z, et al. Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinases. J Biol Chem. 2003 Jul 4;278(27):24944-50.

4.Loux JJ, DePalma PD, Yankell SL. Antipyretic testing of aspirin in rats. Toxicol Appl Pharmacol. 1972 Aug;22(4):672-5.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。