BMS 299897 (BMS299897, γ-Secretase Inhibitor XXIV)是一种磺胺类γ-secretase选择性抑制剂，IC₅₀为12 nM，可抑制Aβ40和Aβ42的形成，但不影响Notch信号传递。

参考文献

1.Weissmiller AM, et al. A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP. PLoS One. 2015 Feb 24;10(2):e0118379.

2.Meunier J, et al. The γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ_1-42 seeding and short-term memory deficits in the Aβ_25-35 mouse model of Alzheimer's disease.Eur J Pharmacol. 2013 Jan 5;698(1-3):193-9.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。