CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.

Flow Cytometry analysis of Human peripheral blood lymphocytes stained with AF488 CD32 antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。