The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.

推荐稀释比 WB:1/500-1/1000;FC:1/50-1/100;ELISA:1/10000

Flow Cytometry analysis of HL-60 cells using CD127 antibody (green) and negative control (red).

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.