Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3β, Dvl, and β-catenin and promotes the GSK-3β-mediated phosphorylation and subsequent degradation of β-catenin .Down-regulates beta-catenin.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of Axin 2 in K562, C6, 3T3, Hela lysates using Axin 2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。