Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.

推荐稀释比 WB:1/500-1/1000;IP:1/50;FC:1/50-1/100

Western blot analysis of LGR5 in mouse brain，rat brain lysates using LGR5 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。