Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival.

推荐稀释比  WB：1/500-1/1000

Western

Western blot analysis of CCDC101 in lysates of HepG2,EL4.IL-2 and BRL using CCDC101 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。