分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
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抑制剂激活剂与常用试剂
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耗材
HP1 alpha Rabbit mAb
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产品介绍
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
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推荐稀释比 WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
应用案例

Western

Western blot analysis of HP1 alpha in C6, PC-12 lysates using HP1 alpha antibody.


Western

Western blot analysis of HP1 alpha in 3T3, Hela lysates using HP1 alpha antibody.


Immunocytochemistry

Immunocytochemistry analysis of HP1 alpha(green) in Hela using HP1 alpha antibody,and DAPI(blue)


Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using HP1 alpha antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.


存储条件

-25 ~ -15℃保存,收到货之后有效期1年,避免反复冻融。

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