CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

推荐稀释比 WB: 1/500-1/1000  IHC: 1/50-1/100

Western

Western blot analysis of CDC25A in 231, A549 lysates using CDC25A antibody

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer using CDC25A antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。