This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants.

Western

Western blot analysis of PELP1 in Hela, A549, MCF-7, 293T lysates using PELP1 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using PELP1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry

Immunocytochemistry analysis of PELP1 (green) in hela using PELP1 antibody,and DAPI(blue)