Antigen binding precedes formation of the CD79A and CD79B heterodimer and subsequent activation of receptor associated kinases. CD79A is a marker for B-lineage lymphoblastic leukemia; mutations in the corresponding mb-1 gene are responsible for abnormally low levels of functional B cell receptors in some cases of chronic B-cell lymphocytic leukemia.

Immunocytochemistry

Immunocytochemistry analysis of CD79a (green) in HL-60 using CD79a antibody,and DAPI(blue).

Western

Western blot analysis of CD79a in Jurkat lysates using CD79a antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil using CD79a antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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