This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Western

Western blot analysis of GALC in mouse brain lysates using GALC antibody

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human gastric cancer using GALC antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.