The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene.

Western

Western blot analysis of ADH1B in Raji lysates using ADH1B antibody

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human tonsil using ADH1B antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.