This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer.

Western

Western blot analysis of KCNA1 in Human brain malignant glioma lysates using KCNA1 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded Human cervical cancer using KCNA1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.