Caspase-2 (Nedd2, ICH-1) is an aspartate-specific cysteine protease that is activated in response to various apoptotic stimuli. Caspase-2 is unique among the caspases in that it has features of both upstream caspases (long prodomain) and downstream caspases (DEXD substrate specificity). Caspase-2 is highly expressed in the brain during development and is expressed at low levels in adult tissue.

Western

Western blot analysis of Caspase2 in Jurkat lysates using Caspase 2 antibody.

Immunohistochemistry

Immunohistochemistry analysis of paraffin-embedded mouse testis using Caspase2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence

Immunofluorescence analysis of Caspase 2 in Hela using Caspase2 antibody.

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