CH-0793076(TP3076)TFA是一种六环喜树碱类似物，作为TP300的活性成分及主要代谢物，能够抑制DNA拓扑异构酶I(IC50=2.3 μM)，并对表达乳腺癌耐药蛋白(BCRP)的细胞具有活性。

[1] Endo M，Miwa M，Ura M，Tanimura H，Taniguchi K，Miyazaki Y，Ohwada J，Tsukazaki M，Niizuma S，Murata T，Ozawa S，Suda H，Ogawa K，Nanba E，Nagao S，Shimma N，Yamada-Okabe H,A water soluble prodrug of a novel camptothecin analog is efficacious against breast cancer resistance protein-expressing tumor xenografts,Cancer Chemother Pharmacol,2010 Jan;65(2):363-71,doi: 10.1007/s00280-009-1042-5,PMID: 19495753.