BMS-470539 dihydrochloride是一种高效、高选择性的黑皮质素1受体（MC1R）激动剂，对MC3R无活性，对MC4R和MC5R的激活作用极弱，具有显著的抗炎特性。
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-25~-15℃避光保存，有效期3年。
[1] Kang L, McIntyre KW, Gillooly KM, Yang Y, Haycock J, Roberts S, Khanna A, Herpin TF, Yu G, Wu X, Morton GC, Tuerdi H, Koplowitz B, Walker SG, Wardwell-Swanson J, Macor JE, Lawrence RM, Carlson KE. A selective small molecule agonist of the melanocortin-1 receptor inhibits lipopolysaccharide-induced cytokine accumulation and leukocyte infiltration in mice. J Leukoc Biol. 2006 Oct;80(4):897-904. doi: 10.1189/jlb.1204748. Epub 2006 Aug 3. PMID: 16888084.
[2]Leoni G, Voisin MB, Carlson K, Getting S, Nourshargh S, Perretti M. The melanocortin MC(1) receptor agonist BMS-470539 inhibits leucocyte trafficking in the inflamed vasculature. Br J Pharmacol. 2010 May;160(1):171-80. doi: 10.1111/j.1476-5381.2010.00688.x. Epub 2010 Mar 19. PMID: 20331604; PMCID: PMC2860217.
