Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).

高纯度、高活性、低内毒素、高批间一致性

                    ELISA  Data

Immobilized Cynomolgus Coagulation factor XI, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-Factor XI Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA.

                    Bioactivity Data

Measured by its ability to cleave the fluorogenic peptide substrate, t-butyloxycarbonyl-Ile-Glu-Gly-Arg-7-amido-4-methylcoumarin (Boc-IEGR-AMC). The specific activity is >50 pmoles/min/μg.

-25 ~ -15℃保存，收到货之后有效期1年。
复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。