Moxifloxacin Hydrochloride (BAY 12-8039)是一种口服有效的8-甲氧基喹诺酮类抗菌剂,其研究应用于急性细菌性鼻窦炎、慢性支气管炎急性加重及感染性肺炎。
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英文别名 (English Synonym) |
Moxifloxacin HCl |
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中文名称 (Chinese Name) |
莫西沙星盐酸盐 |
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靶点 (Target) |
Topoisomerase |
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通路 (Pathway) |
Cell Cycle/DNA Damage |
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CAS号 (CAS NO.) |
186826-86-8 |
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分子式 (Formula) |
C21H24FN3O4·HCl |
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分子量 (Molecular Weight) |
437.89 |
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纯度 (Purity) |
≥98% |
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溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Grayo S, Join-Lambert O, Desroches MC, Le Monnier A. Comparison of the in vitro efficacies of moxifloxacin and amoxicillin against Listeria monocytogenes. Antimicrob Agents Chemother. 2008 May,52(5):1697-702. doi: 10.1128/AAC.01211-07. Epub 2008 Feb 25. PMID: 18299415, PMCID: PMC2346626.[2]Ioannidis O, Papaziogas B, Tsiaousis P, Paraskevas G, Giamarellos-Bourboulis EJ, Koutelidakis I. Effect of moxifloxacin on survival, lipid peroxidation and inflammation in immunosuppressed rats with soft tissue infection caused by Stenotrophomonas maltophilia. Microbiol Immunol. 2014 Feb,58(2):96-102. doi: 10.1111/1348-0421.12124. PMID: 24372798.
