Nepafenac (AHR 9434, AL 6515, Nevanac, AHR9434, AL6515)，又称奈帕芬胺，是非甾体抗炎药剂，是COX-2抑制剂，作用于COX-1/2的IC₅₀值分别为250 nM和150 nM，能阻断前列腺素的合成，临床上常用于治疗白内障手术引起的眼部疼痛和炎症。

参考文献

[1] Ke TL, Graff G, Spellman JM, Yanni JM. Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma-induced ocular inflammation: II. In vitro bioactivation and permeation of external ocular barriers. Inflammation. 2000 Aug;24(4):371-84.

[2] Gamache DA, Graff G, Brady MT et al. Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma-induced ocular inflammation: I. Assessment of anti-inflammatory efficacy. Inflammation. 2000 Aug;24(4):357-70.

[3] Kern TS, et al. Topical administration of nepafenac inhibits diabetes-induced retinal microvascular disease and underlying abnormalities of retinal metabolism and physiology. Diabetes. 2007 Feb;56(2):373-9.

冰袋运输。粉末直接保存于-25~-15℃，有效期3年。建议分装后-25~-15℃干燥保存，避免反复冻融。