Ketoprofen (RP-19583, RP19583)，又称酮洛芬，是一种非甾体抗炎镇痛药，耐受性好、毒副作用轻，是双重COX1/2抑制剂，IC₅₀分别为0.5 μM和2.33 μM，减少促炎前列腺素前体的产生，进而表现出抗炎、镇痛和解热作用，临床上广泛用于治疗各种关节炎。

参考文献

1.Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12(4):533-7.

2.NamHyeon Kang Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway. Pflugers Arch. 2020 May;472(5):583-596.

3.Denisa Dan, et al. Ketoprofen affects the mammary immune response in dairy cows in vivo and in vitro. J Dairy Sci. 2018 Dec;101(12):11321-11329.

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。