Itacitinib (INCB39110, INCB-39110)，又称伊他替尼，是一种有效的JAK1选择性抑制剂，选择性比对JAK2高20倍，比对JAK3和TYK2高100倍，具有抗肿瘤活性，也可用于骨髓纤维化的研究。

参考文献

1.Mascarenhas JO, et al. Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis. Haematologica. 2017 Feb;102(2):327-335.

2.Jun Li, et al. Abstract 779: Blockade of the IL-6/JAK/STAT3 signaling pathway inhibits pancreatic tumor cell growth in 3D spheroid cultures and in xenograft models. AACR; Cancer Res. 2015, 75(15 Suppl).

冰袋运输。粉末直接保存于-20℃，有效期3年。建议分装后-20℃干燥保存，避免反复冻融。