TTNPB芳香维甲酸(Ro 13-7410,AGN-191183) RAR激动剂|CAS 71441-28-6（53242ES）

TTNPB (Arotinoid Acid, Ro 13-7410, AGN-191183, AGN191183)，又称芳香维甲酸，是有效的RAR激动剂。TTNPB通过结合核视黄酸受体，抑制RAR与[³H]tRA结合。TTNPB对hRARα/β/γ的C₅₀分别为5.1 nM、4.5 nM和9.3 nM。此外，TTNPB是一种致畸剂，还能增强化学诱导的多能干细胞(CiPSC)的重编程效率。

参考文献

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