分子生物学
IVD分子诊断
细胞培养与分析
蛋白研究
细胞因子
重组蛋白
抗体
高通量测序建库
病原检测UCF系列
生物医药
工具酶
抑制剂激活剂与常用试剂
仪器
耗材
Recombinant Human GCGR/Glucagon receptor Protein,His Tag
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产品介绍
The pancreatic hormone glucagon activates the glucagon receptor (GCGR), a class B seven-transmembrane G protein-coupled receptor that couples to the stimulatory heterotrimeric G protein and provokes PKA-dependent signaling cascades vital to hepatic glucose metabolism and islet insulin secretion. The GCGR expressed at the plasma membrane is constitutively ubiquitinated and upon agonist-activation, internalized GCGRs are deubiquitinated at early endosomes and recycled via Rab4-containing vesicles.
产品性质
产品特色
高活性、高纯度、低内毒素、高稳定性
应用案例
ELISA Data: Immobilized Human GCGR, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-GCGR Antibody, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA.
存储条件
-25~-15℃保存,收到货之日起,有效期1年。复溶后, -85~-65℃保存,3个月有效期。避免反复冻融。
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