重组生物素化小鼠CD47蛋白(His和Avi标签) Recombinant Biotinylated Mouse CD47 Protein,His&Avi Tag(96521ES)
Recombinant Biotinylated Mouse CD47 Protein,His&Avi Tag
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产品应用
产品介绍
CD47, also known as Integrin-associated protein (IAP), is a typical representative of the "marker of self" of targets expressed by all types of cells. CD47 is a glycoprotein with an immunoglobulin variable N-terminal domain, five transmembrane domains, and a short C-terminal intracellular tail with four variably different splicing isomers, resulting in four isoforms. CD47 is an immune cell group that plays a major role in targeted tumor immunotherapy. CD47 expressed by cancer cells interacts with SIRP-α and SIRP-γ expressed by NK cells to protect cancer cells from phagocytosis and elimination. CD47 was highly expressed in a variety of solid tumor cells and malignant hematoma cells, and its expression level was positively correlated with disease progression. . CD47 is a glycoprotein with an immunoglobulin variable N-terminal domain, five transmembrane domains, and a short C-terminal intracellular tail with four variably different splicing isomers, resulting in four isoforms . CD47 is an immune cell group that plays a major role in targeted tumor immunotherapy
产品性质
产品特色
高活性、高纯度、低内毒素、高批间一致性
存储条件
-25 ~ -15℃保存,收到货之后有效期1年。
复溶后,无菌条件下,2~8℃保存,7天有效期。复溶后, 无菌条件下,-85 ~ -65℃保存,6个月有效期。
COA
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