SN52是含p50核定位序列(NLS)的细胞通透性肽，作为SN50肽的变体，它是具竞争性的NF-κB2选择性抑制剂。其可选择性阻断电离辐射诱导的p52和RelB核输入，抑制p52-RelB异二聚体核易位，且能强效增强前列腺癌细胞的放射敏感性，是癌症研究中的重要工具分子。

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