Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

推荐稀释比 WB:1/1000-1/2000; IHC:1/100-1/200; IF:1/50-1/200; FC:1/50-1/100

Western blot analysis of PARP in Jurkat and Hela lysates using PARP1 antibody.

Immunofluorescence analysis of PARP1 in Hela using PARP antibody.

Western blot analysis of PARP in Jurkat lysates using PARP1 antibody

Immunohistochemistry analysis of paraffin-embedded Human testis using PARP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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