This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

推荐稀释比 WB:1/500-1/1000; ICC/IF:1/20; FC:1/20-1/50; IP:1/20

Immunocytochemistry analysis of SQSTM1/p62 (green) in U87-MG using SQSTM1/p62 antibody,and DAPI(blue).

Western blot analysis of SQSTM1/p62 in A549, HL-60, U2OS lysates using SQSTM1/p62 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。