High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, members of the NFκB family, ATF-2 and c-Jun to activate transcription.

推荐稀释比 WB:1/1000-1/2000; IHC:1/100-1/200; IF:1/50-1/200; FC:1/50-1/100

Western blot analysis of HMGB1 in mouse brain，rat brain，hela lysates using HMGB1 antibody.

Western blot analysis of HMGB1 in (1)HeLa lysates; (2)Rat brain lysates using HMGB1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human kidney using HMGB1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of HMGB1 in SW48 using HMGB1 antibody.

Western blot analysis of HMGB1 in HCT116, MCF-7 and Jurkat lysates using HMGB1 antibody.

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