Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.

推荐稀释比 WB:1/1000-1/2000; IHC:1/100-1/200; FC:1/50-1/100; IP:1/50

Western blot analysis of Bax in (1) HeLa lysates;(2) RAW264.7 Whole lysates using Bax antibody.

Immunohistochemistry analysis of paraffin-embedded Human adenocarcinoma of colon using Bax antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Bax in THP-1 and Hela lysates using Bax antibody

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。