DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.

Flow Cytometry analysis of C57BL/6 murine bone marrow cells stained with CD49b antibody (APC). Unstained bone marrow cells (empty black histogram) are used as control.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。