Human CD39 is an integral membrane protein with two transmembrane domains. It exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen. Product Details

推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.

Flow Cytometry analysis of Human peripheral blood lymphocytes stained with APC CD39 antibody (filled gray histogram) or mouse IgG1 Isotype Control APC (empty black histogram).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。