CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells,B cells,and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages.CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues.CD200 is the ligand for CD200 receptor (CD200R).The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity.Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.

推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.

Flow Cytometry analysis of C57BL/6 murine splenocytes stained with(APC) CD200 antibody and (FITC) CD45R/B220 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。