Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

推荐稀释比 WB:1/500-1/1000;ELISA:1/10000

Western blot analysis of Phospho-JAK2/3 (Tyr966/939) in mouse liver, hela , mouse brain lysates using Phospho-JAK2/3 (Tyr966/939) antibody.

Western blot analysis of Phospho-JAK2/3 (Tyr966/939) in hela lysates using Phospho-JAK2/3 (Tyr966/939) antibody.

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