The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

推荐稀释比 IHC:1/50-1/100

Immunohistochemistry analysis of paraffin-embedded human pancreas using GEMIN8 antibbody. High-pressure and temperature Accel 3in1 EDTA pH 8.7 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human pancreas tissue using GEMIN8 antibbody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.