This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

推荐稀释比 IHC:1/50-1/100

Immunohistochemistry analysis of paraffin-embedded Human pancreas tissue using DDX56 antibbody. High-pressure and temperature Tris-EDTA pH 9.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human lymphoma tissue using DDX56 antibbody. High-pressure and temperature Tris-EDTA pH 9.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.