This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

推荐稀释比 IHC:1/100-1/200;IF:1/50-1/200

Immunocytochemistry analysis of SOX2 in NTERA-2 cells using SOX2 antibody (green). Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。