Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3. Transcriptional activator of MBP, via binding to the gene promoter.
推荐稀释比 WB:1/500-1/1000;IHC-P:1/50-1/100;ICC/IF:1/50

Western blot analysis of SOX10 in lysates of A375 using SOX10 antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast using SOX10 antibody.High pressure and temperature Tris/EDTA (PH 9.0) used for antigen retrieval.The brown color represents the positive signal observed with SOX10 antibody.

Immunocytochemistry analysis of SOX10(green) in A375 cells using SOX10 antibody,and DAPI(blue).
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