Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

推荐稀释比 WB:1/500-1/1000;IP:1/40

Western blot analysis of BACE1 in Rat brain，mouse brain lysates using BACE1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。