Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy. Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding .

推荐稀释比 WB:1/500-1/1000;IP:1/20

Western blot analysis of HOPX/HOD in Hela lysates using HOPX antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。