Products of the highly conserved Wnt gene family, including Wnt-1 through Wnt-10, play key roles in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of Wnt2/IRP in Human endometrial cancer lysates using Wnt2/IRP antibody.

Immunohistochemistry analysis of paraffin-embedded Human prostate cancer using Wnt2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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